Advancing healthcare through clinical trials
Clinical trials are a vital part of our mission to advance cancer research and improve patient outcomes. These trials, conceived and led by researchers and clinical investigators, explore innovative treatments and interventions that are directly informed by laboratory discoveries and clinical expertise. By bridging scientific research with patient care, we bring new hope and improved therapies to those who need them most.
We prioritise sponsoring unique investigator-led trials across all oncology disciplines, including medical oncology, haematology, imaging, palliative and radiation oncology. By supporting clinician-led research, we help drive discoveries that translate directly into better patient care and improved treatment strategies.
Why partner with us?
Since 2016, the ONJCRI Clinical Trials Unit (CTU) has provided high-quality resources and infrastructure to support and conduct clinical trials.
Located within the Olivia Newton-John Cancer Centre at Austin Health, we bridge ONJCRl's world-class laboratory research with clinical teams and suitable patients. We work closely with hospitals, universities, and research partners across Australia and internationally. Our collaborative approach fosters innovation and accelerates the development of new treatments.
Our experienced team of clinicians, project managers and clinical research associates enables us to sponsor and manage both single and multi-site studies across Australia and New Zealand.
Recognising that every trial is unique, we offer flexible, tailored services to meet the specific needs of our research partners. Whether you require full-service trial management or select support services, we provide customised solutions to ensure efficient and high-quality trial execution.
All clinical research is approved by a Human Research Ethics Committee and complies with to all applicable Australian laws and regulations. This includes compliance with ICH GCP, The National Statement on Ethical Conduct in Human Research 2023 and the Australian Code for the Responsible Conduct of Research.
Our services
We offer a comprehensive suite of services to support and manage clinical trials effectively:
- Protocol Development
- Regulatory compliance and submissions
- Budget Development and Financial Management
- Sites Selection and Support
- Project Management, Data Management and Study Coordination
- Monitoring and Quality Assurance
- Safety and Pharmacovigilance
- Biospecimen Coordination
- Clinical Trial Supplies Management
Our clinical trials
I-FIRST
Recruiting
This prospective, non-randomised phase II trial aims restore radioiodine sensitivity in patients with NRAS or BRAFV600E mutant refractory Thyroid Cancer.
START-HN
Recruiting
This aim of this trial is to compare the immune responses within Head and Neck Cancer tumours which have and have not been treated with stereotactic ablative body radiotherapy (SBRT).
RESONANCE
Recruiting
This trial is assessing the effect of medicinal cannabis on quality of life and symptom control in advanced cancer.
BIL-PPP
Recruiting
This trial is evaluating maintenance durvalumab & olaparib in patients with advanced Cholangiocarcinoma after initial chemotherapy and durvalumab.
VIGOR
Active – Recruiting
This trial is investigating the benefits of vorasidenib in patients with grade II / III gliomas.
MOST-CIRCUIT
Active - Not Recruiting
This clinical trial is evaluating the benefit of combining nivolumab and ipilimumab in immunotherapy-sensitive Rare Cancers.
FLUORO
Active - Not Recruiting
This trial is assessing response and toxicity of obinutuzumab & atezolizumab, with/without radiotherapy, in treatment-naive Follicular Lymphoma.
TOP-FLOR
Active - Not Recruiting
This trial is exploring first line treatment with combination rituximab and golcadomide with, or without nivolumab, in patients with previously untreated Follicular Lymphoma.
RICE
Active - Not Recruiting
This trial is investigating the feasibility of pre-operative high-dose radiation in early Breast Cancer patients.
VADER
Active - Not Recruiting
This trial is assessing sodium valproate with anti-EGFR maintenance therapy in first-line treatment of RAS wild-type metastatic Bowel Cancer.
PIRC
Active - Not Recruiting
This trial is assessing a new type of positron emission tomography (PET) scan, targeting prostate specific membrane antigen (PSMA), in patients with metastatic Kidney Cancer.
Meet our clinicians
We are proud to have a passionate team of clinicians dedicated to delivering high-quality clinical trials. Their expertise and commitment ensure that each trial is conducted with the upmost care, scientific rigour, and a focus on improving patient outcomes. Through close collaboration with researchers and a shared drive for advancing medical knowledge, they help bring innovative treatments to those who need them most.
Our dedicated team
Our team of clinical research support professionals includes:
