Postdoctoral Research Fellow

Full time and Maximum Term

  • Exciting postdoctoral research opportunity with newly established lab
  • Full time and fixed term for 12 months
  • Generous staff benefits including salary packaging to $18,550

The Olivia Newton-John Cancer Research Institute (the Institute) is a leader in the development of experimental and breakthrough cancer treatments. We investigate and develop treatments for cancers of the breast, bowel, lung, melanoma, prostate, liver, gastrointestinal tract and brain.


Our priority is to outsmart cancer.

Our vision is to help people live better with cancer and defeat it.

Our mission is to discover and develop breakthrough cancer therapies to provide the best health outcomes for patients.


About the position

The Postdoctoral Research Fellow position is based within the Tumour Progression and Heterogeneity Laboratory of the  Cancer Biology and Therapy Program. The laboratory aims to understand the biological properties of cancer clones, to prevent their dissemination and design new combination therapies for the treatment of advanced disease.

Key Responsibilities include:

  • Support the Lab’s aim at identifying the mechanisms associated with tumour progression and drug resistance
  • Laboratory research, including but not limited to:
    • Track the cellular and molecular events associated with tumour expansion in metastatic disease, taking into consideration the impact of the tumour microenvironment
    • Develop new pre-clinical models of breast cancer for drug discoveries
  • Be able to work on a suite of projects which investigate the cellular and molecular basis of cancer progression and drug resistance using cancer cell lines, patient samples and mouse models. In brief, the work will involve a range of emerging technologies such as single cell sequencing, cellular barcoding and imaging
  • Develop an innovative research program based on these themes, publish the work in a timely manner, secure ongoing funding and initiate experiments and collaborations necessary to achieve the successful completion of this project
  • Collaborate with other members of the team and external researchers.
  • Present data in internal/external meetings, and at national and international conferences.
  • Commitment to training and supervision of other group members, including staff and students (Honours/PhD).
  • Seek competitive external funding and contribute to the writing of grant applications.
  • Writing of successful application to the relevant OGTR and Animal Ethics Committee(s).
  • Participate and support engagement activities within the institute and the wider cancer biology community.


About you

The successful candidate must be self-motivated and independent, possess an enquiring mind with exceptional organisational and time management skills,. You hold yourself to a high standard and expect optimal performance of yourself and your team.

In addition, you must have the following:

  • A PhD in cellular or molecular biology
  • Flow cytometry (staining and analysis)
  • Working with mouse models
  • Microscopy and in vivo imaging
  • Tissue culture (cell culture, virus production, transfection, and infection)
  • Molecular biology (Cloning / western blot analysis / immunohistochemistry / RT-PCR / DNA and RNA sequencing)
  • Computer skills (Word processing, PowerPoint, Excel, database use, EndNote, Illustrator, Prism) and data analysis skills (optional)
  • Excellent publication record (first author papers)
  • Experience with writing grants and ethics applications
  • Ability to manage multiple priorities and a demanding schedule
  • Good interpersonal and communication (both written and verbal) skills
  • Excellent planning and organisational skills
  • Excellent attention to detail
  • Demonstrated ability to mentor / supervise junior research members
  • Ability to work to the highest ethical and professional standards

We offer workplace benefits including generous salary packaging benefits to $18,550 per FBT year and 4 extra Institute Days off each year.


To Apply:

Please forward your completed application, quoting reference number ONJCRI-092/2022 to Associate Professor Delphine Merino, Tumour Progression and Heterogeneity Lab, at, with the following information:

  • Your cover letter, stating why you would be a good fit for the role;
  • Your CV;
  • 3 referee details (referees will only be contacted after interview).

The Institute is committed to creating a diverse and inclusive work environment and workforce and we strongly encourage people from all backgrounds to apply.

Closing date: 5 December 2022